Zeel® has been researched for over 40 years and has been used extensively by patients in approximately 20 countries. Each year, hundreds of thousands of patients are treated with Zeel® to treat degenerative joint disease. Zeel® is produced in Germany by Biologische Heilmittel Heel GmbH and distributed in 20 countries worldwide.
In Greece, Zeel® was granted a marketing authorization as an OTC medicine and is available in pharmacies from the company A.S.K. Pharmaceutical in two easy-to-use formulations: tablet and cream. Zeel® tablet1 is used to relieve the symptoms of pain and inflammation of the joint damage associated with arthropathy. Zeel® cream2 is used topically for the symptomatic treatment of arthropathy pain.
Each individually inhibit both LOX-5 and COX (COX-1 and COX-2)
Inhibits COX (COX-1 and COX-2), inhibits prostaglandin biosynthesis and PAF induced exocytosis.
Suppresses the proliferative effect of VEGF on endothelial cell line, probably mediated by blocking the VEGF-induced Akt activation.