Neurexan ®

Neurexan® is produced in Germany and marketed by Biologische Heilmittel Heel GmbH since 2003 and marketed in Greece by A.S.K. Pharmaceutical as an OTC medicine in tablet formulation.1

Neurexan® is a carefully formulated, systematically produced and clinically controlled multi-ingredient combination of four herbal and mineral components and is indicated for the supportive treatment of nervous restlessness and associated sleep disorders in adults with mild to moderate restlessness.(If you have symptoms of depression, you should consult your doctor before using Neurexan®).1

Patient Instructions Leaflet


Natural treatment for nervous restlessness and associated sleep disorders.

Zincum Isovalerianicum

Against nervousness and sleep disorder.2,3

Passiflora Incarnata

Against nervousness and sleep disorder.2,3,4

Avena Sativa

Against burnout and sleep disorder.2,3,5

Coffea Arabica

Against insomnia.2,3


Patients with mild to moderate insomnia.

Non addictive.

No dizziness or drowsiness during the day.

No drug interactions.

Health professionals

  • Neurexan Leaflet
  • Citations
Neurexan Leaflet
  1. Product approved by EOF-Marketing Authorization Number 33899/17 / 28-06-2018
  2. Göthel D. Neurexan® : The bioregulatory approach to the treatment of stress and stress-related disorders—preclinical and clinical considerations. Altern Ther. 2011;17(Suppl 2):S32-S40.
  3. Reckeweg H-H.Materia Medica: Homoeopathia Antihomotoxica Baden-Baden: Aurelia Verlag Gmbh; 2002
  4. European Medicines Agency. Community herbal monograph on Passiflora incarnata L., herba.March 2014
  5. European Medicines Agency. Community herbal monograph on Avena sativa L., herba. September 2008.
  6. Doering BK, Wegner A, Hadamitzky M, Engler H, Rief W, Schedlowski M. Effects of Neurexan® in an experimental acute stress setting-An explorative double-blind study in healthy volunteers . Life Sci. 2016;146:139-147.
  7. Waldschutz R, Klein P. The homeopathic preparation Neurexan® vs valerian for the treatment of insomnia: an observational study. Scientific World Journal. 2008;8;411-420.
  8. Hübner R, van Haselen R, Klein P. Effectiveness of the homeopathic preparation Neurexan® compared with that of commonly used valerian-based preparations for the treatment of nervousness/restlessness-an observational study. Scientific World Journal. 2009;9;733-745.

Report side effects

  • How can I report side effects?
How can I report side effects?

Healthcare professionals are asked to report any suspected adverse reactions via the National Organization of Medicines. If you are a patient and you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in the package leaflet. You can report adverse reactions with the following options :
1) Electronic submission through EOF’s website
2) Dispatching the Yellow card in hard copy via mail to EOF to the Department of Adverse Reactions (Mesogeion 284, Cholargos 15562)
3) Communication with the Department of Adverse Reactions via telephone :
4) Submission of the yellow card via fax at 210.6549.585


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